- A naloxone injection directly into the muscle of the upper thigh or upper arm.
- Auto injector – Evizio:
- A ready-to-use, automatic injection device, which gives electronic voice-guided, step-by-step instructions. Note, this version is typically very expensive (around $4000) and may not be covered by some insurances.
- Prepackaged Nasal Spray – Narcan Nasal Spray:
- A preassembled, ready-to-use device. After the nasal spray nozzle is gently inserted into the person’s nostril, firmly press the plunger to spray one entire dose into one nostril. The naloxone is absorbed into the bloodstream so there is no need for the person to inhale it for the medication to work.
- Nasal Atomizer:
- A pre-filled cartridge of naloxone and a nasal atomizer that requires assembly. Note, this device is not FDA approved.
Naloxone can also be administered intravenously (through an IV) by medical professionals.