Medication Assisted Treatment (MAT) in combination with behavioral therapies to treat opioid use disorders helps reduce rates of illicit use and overdose by reestablishing normal brain functioning, reducing drug cravings, and preventing relapse (Kampman et al., 2015). MAT also lowers the risk of contracting infectious diseases (Tsui et al., 2014; Metzger et al., 1993). Research supports the perspective that opioid addiction is a chronic medical disorder that can be treated effectively with medications and supportive services such as psychosocial counseling, treatment for co-occurring disorders, motivational counseling, and vocational rehabilitation (SAMHSA, 2005).
Below is a link to: “COVID-19 and OUD in Missouri: Changes in practice within EMS, hospitals, and addiction treatment settings” – a topic-specific webinar roundtable to exchange ideas on best practices that could broadly apply to any area getting hit by COVID-19 and uncertain how to adapt substance-use related protocols. This webinar features experts from hospital, EMS, and Substance Use Disorder (SUD) treatment settings to briefly highlight how they have adapted policies and practices handling overdose/treatment in the COVID era. The goal would be spreading knowledge about best approaches around Missouri. Brought to you by the Missouri Overdose Prevention and Response Collaborative through the MO-HOPE, MORE, SOR, and Connecting the DOTS grants.
For more information on Medication Assisted treatment, visit:
SAMHSA- Medication Assisted Treatment
PCSS-MATT- Medication Assisted Treatment
Missouri Department of Mental Health – Medication Assisted Treatment
Medication-Assisted Treatment Improves Outcomes for Patients with Opioid Use Disorder
American Association for the Treatment of Opioid Dependence – Resources
The primary medications used to treat OUD are:
*Information provided on this site is not intended to cover everything –there are many places to find helpful information about opioid use disorder treatment. To learn more, we suggest visiting the following sites:
For information on available drug treatment:
- Visit the SAMHSA Treatment Locator or call the National Helpline 1-800-662-HELP or 1-800-487-4889 (TDD-for hearing impaired)
- Visit SAMHSA Treatment Provider Locator to locate buprenorphine prescribers near you
- Visit SAMHSA Behavioral Health Treatment Services Locator to search by address, city or zip code
- Visit Prevent+Ed- Find Help or call 314-962-3456 to talk to a counselor for information, support, arrange an assessment or receive referrals.
- Visit MO Network for Opioid Reform- Outreach Center to schedule an appointment or MO Network for Opioid Reform- Get Help for treatment referrals or intervention requests
- Visit MO Department of Mental Health-How to Get Help for directories of treatment programs
- For additional resources to locate opiate rehab centers and programs, visit http://www.opiate.com/drug-rehab/ or call the 24-hour addiction hotline at 800-584-3274
Below are links to a small subset of research conducted on opioid use disorder treatment. For a more comprehensive reference list, please see: Overdose Prevention Alliance and CTN Dissemination Library
Long term retention in Office Based Opioid Treatment with buprenorphine
Models of Integrated Patient Care through OTPs and DATA 2000 Practices
For Buprenorphine Waiver- Medication-Assisted Treatment Trainings offered throughout the state of Missouri, visit here.
For training, webinars, toolkits and additional resources related to addressing opioid misuse, visit: Taking Action to Address Opioid Misuse , Reducing Substance Use Disorders, and Opioid Use, Misuse, and Overdose in Women