Research and Data

Providing overdose education and naloxone distribution (OEND) in various settings (i.e., emergency departments, primary care, prisons/jail, treatment facilities, community centers, etc.) has been strongly recommended by the CDC , World Health Organization , and the American Society of Addiction Medicine based on empirical evidence. This page is not intended to cover everything, but is designed to connect you with some of the research literature and data related to opioid overdose mortality and morbidity, prevention and intervention initiatives, policy impact, and more.

For updated systematic reviews of Overdose Education and Naloxone Distribution Programs, Legal Research and literature on opioid overdose prevention, visit Prescribe to Prevent.

For publications and reports on naloxone and harm reduction, visit:

For publications and resources on drugs and drug policy, visit:

For additional information, visit the SAMHSA publications on opiates/opioids, heroin, prescription drugs, buprenorphine, methadone, and treatment, prevention and recovery